Transgenic Animals Applications Ppt

Transgenic animals produced with.

Transgenic animals applications ppt. Methodology and Applications - Chapter 21-Transgenic Animals. Transgenic animals was started using sperm mediated gene transfer. Let us have a detailed look at the process importance and applications of transgenic animals.

Transgenic animals that produce useful biological products can be created by the introduction of the portion of DNA or genes which codes for a particular product such as human protein a-1-antitrypsin used to treat emphysema tissue plasmogen activator goat blood clotting factors VIII and IX sheep and lactoferrin cow. These bacteria contained genetic information from a variety of different species. Methodology and Applications Transgenic mice.

There are several methodologies employed in producing transgenic animals. 356 have been used as experimental animals for production of transgenic fish. Transgenic Animals Synthetic modified or other foreign genes can be introduced into animals and plants and the resulting transgenic organisms can be used to study the function of the genes for example by insertional mutagenesis to produce novel products or to serve as animal models for studies of inherited human diseases.

One of the most exciting prospects for the genetic manipulation of chickens is the potential development of an embryonic stem ES-cell system. Methodology Retrovirus vector DNA microinjection Engineered embryonic stem cell Cre. The first genetically modified organism was engineered in the year 1980.

DNA Technology Biotechnology The use or alteration of cells or biological molecules for specific applications Transgenics Transgenic changed genes Recombinant DNA DNA from different species mixed together Natural or man-made Whole organisms or cells Possible because the genetic code is universal All life uses the same genetic code ATGC Amplifying DNA Need. Transgenic animals can be used as disease models transpharmers xenotransplanters food sources and other biological models. The development of transgenic animals has been part of biotechnology research which has been expanding rapidly.

A transgenic animal is one that carries a foreign gene that has been deliberately inserted into its genome. This would enable not only the addition of gene constructs but. A transgenic animal has been genetically engineered to incorporate a foreign gene.