Transgenic Animals Online Biology Notes
The foreign gene is constructed using recombinant DNA methodology.
Transgenic animals online biology notes. Organisms containing integrated sequences of cloned DNA transgenes transferred using techniques of genetic engineering to include those of gene transfer and gene substitution are called transgenic animals. By DAMARIS BENNY DANIEL II Msc. Its body is almost bell-shaped or campanulate with a free anterior end surrounded by cilia.
Transgenic animals are created-To study how genes are regulated and how they affect the normal functions of the body and its development. Clinical cultural and Biochemical diagnosis. Example- Transgenic rats rabbits pigs sheep etc.
The dependence of man on animals such as cattle sheep poultry pig and fish for various purposes milk meat eggs wool etc is well known. The commonest species is Vorticella campanula. In addition to the gene itself the DNA usually includes other sequences to enable it to be incorporated into the DNA of the host and to be expressed correctly by the cells of the host.
The Human Genome Project revealed that the human genome contains only 20000 to 25000 genes. Transgenic animals represent unique models that are custom tailored to address specific biological questions. Toxicity testing in such animals will allow us to obtain results in less time.
The DNA that is introduced Transgenesis. This article provides an overview on transgenic animals. Transgenic animals are used as tools in research and for the production of recombinant proteins The main applications of transgenic animals are described as followsStudying gene function.
These are the animals whose genome has been altered by introduction of a foreign gene by manipulation. The procedure is the same as that used for testing toxicity of drugs. The animal production industry is gradually reaching towards revolution due to the development of genetic map knowledge of expression of genes and techniques for large propagation.